Selective antimicrobial modulation of the intestinal flora

Selective antimicrobial modulation of the intestinal flora of patients with acute nonlymphocytic leukemia: a double-blind, placebo-controlled study.

Thirty-three patients with acute nonlymphocytic leukemia were studied during remission-induction treatment in a double-blind, placebo-controlled, randomized study to ascertain the effect on the incidence of infection of an oral regimen of selective antimicrobial modulation (SAM). A decrease in the number of major acquired infections was observed: three infections occurred in 16 patients receivi...

Selective Antimicrobial Modulation of the Intestinal Microbial Flora for Infection Prevention in Patients with Hematologic M alignancies

Intestinal Flora and Nutrition

Sir,?There is one aspect of study in nutrition which does not yet appear to have been accorded its true value. I refer to the part played by the organisms living inside the alimentary tract of man. To the majority studies on nutrition end at the stage at which the food is Swallowed. Others, more exact, define conditions in which absorption of the ultimate products of digestion is disturbed as f...

Intestinal flora and diet

The topics discussed at the WIRM-V meeting were very broad and interesting, covering a wide field in immunology. Since it is impossible to summarize everything, I will discuss the influence of diet and intestinal flora on immune responses, as this was a recurrent subject throughout the meeting. I will summarize a few presentations (given by E.G. Pamer, C. MacKay, D.R. Littman, Y. Belkaid, R. Ma...

Modulation of the intestinal flora of mice by parenteral treatment with broad-spectrum cephalosporins.

A study was performed to determine the effect of parenteral treatment with four broad-spectrum cephalosporins (cefoperazone, ceftriaxone, ceftazidime, and cefepime) on the number of aerobic gram-negative rods and on the outgrowth of Candida albicans and a multiresistant strain of Citrobacter freundii in the feces of mice. The estimated fractions of a parenteral dose that were excreted into the ...